UTP18

Across TCGA cell cohorts, UTP18 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UTP18-associated genes across cancer lineages are SLCO1B7, COX4I2, and GSG1L2. Each is linked with UTP18 in more than 1 cancer types. Because this analysis shows association rather than direction, both UTP18-to-partner and partner-to-UTP18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLCO1B7 grouped by UTP18-low versus UTP18-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP18→partner) and Y-score (partner→UTP18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLCO1B7 →	+0.101	+4.874	<.001	.002	3	1
LUNG_NSCLC_LUAD	COX4I2 →	+0.095	+5.228	<.001	.005	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

SLCO1B7 by UTP18 expression — BLOOD_Leukemia

Explore this box plot interactively →