UTP15

Across TCGA pan-cancer cohorts, UTP15 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UTP15 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher UTP15 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated UTP15 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

CCRCC, LSCC, and PDAC are the cancer types where UTP15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.360	0.753	<.001	94	view →
LSCC	DFS	Tertile	II,III,IV	0.896	0.506	.008	13	view →
PDAC	OS	Quartile	II,III,IV	0.342	0.701	.006	10	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	9	view →
GBM	OS	Median	All	0.606	0.453	.017	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UTP15–CCRCC (DFS)

Open the CCRCC breakdown →