UTP15

Across TCGA patient cohorts, UTP15 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UTP15-associated genes across cancer lineages are JNK2, ATM, and FoxM1. Each is linked with UTP15 in more than 1 cancer types. Because this analysis shows association rather than direction, both UTP15-to-partner and partner-to-UTP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by UTP15-low versus UTP15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP15→partner) and Y-score (partner→UTP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.297	+2.700	<.001	.006	3	2
UCEC	ATM →	-0.523	-3.156	.010	.018	3	2
UCEC	FoxM1 →	+0.362	+2.700	.001	.006	3	1
UCEC	G6PD →	-0.296	-2.000	.042	.032	3	1
UCEC	GATA6 →	-0.154	-2.321	.032	.034	3	1
UCEC	INPP4B →	-0.357	-2.321	.014	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

JNK2 by UTP15 expression — UCEC

Explore this box plot interactively →