UTP15

Across TCGA cell cohorts, UTP15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,907 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UTP15-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Regulation of rRNA processing, and Maturation of SSU-rRNA. Each is linked with UTP15 in more than 19 cancer types. Because this analysis shows association rather than direction, both UTP15-to-partner and partner-to-UTP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by UTP15-low versus UTP15-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP15→partner) and Y-score (partner→UTP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of rRNA processing →	+0.151	+1.127	<.001	<.001	3	20
OESOPHAGUS	Regulation of rRNA processing →	+0.137	+1.299	.002	.001	3	20
OESOPHAGUS	Maturation of SSU-rRNA →	+0.180	+1.361	<.001	<.001	3	18
BONE	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.123	+0.545	.001	.004	3	18
BONE	rRNA 5'-end processing →	+0.123	+0.545	.001	.004	3	18
PANCREAS	Transcription by RNA polymerase I →	+0.106	+0.634	<.001	.004	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,907 associations by consensus.

Positive regulation of rRNA processing by UTP15 expression — BLOOD_Lymphoma

Explore this box plot interactively →