UTP14A

Across TCGA patient cohorts, UTP14A mutation is significantly associated with the RNA expression of many other genes, with 4,937 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UTP14A-associated genes across cancer lineages are RNA5SP436, MCAT, and ZNF330. Each is linked with UTP14A in more than 2 cancer types. Because this analysis shows association rather than direction, both UTP14A-to-partner and partner-to-UTP14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP436 grouped by UTP14A-low versus UTP14A-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP14A→partner) and Y-score (partner→UTP14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP436 →	+0.297	+4.295	<.001	.006	3	3
UCEC	MCAT →	+0.417	+2.705	<.001	<.001	3	3
UCEC	ZNF330 →	+0.461	+1.699	<.001	<.001	3	3
UCEC	TTC19 →	+0.559	+2.321	<.001	<.001	3	3
BLCA	BMS1P11 →	+0.071	+2.589	.005	.009	3	3
HNSC	RN7SKP230 →	+0.296	+3.286	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,937 associations by consensus.

RNA5SP436 by UTP14A expression — LUSC

Explore this box plot interactively →