UTP14A

Across TCGA patient cohorts, UTP14A mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UTP14A-associated genes across cancer lineages are Caspase-7-cleavedD198, c-Kit, and FoxM1. Each is linked with UTP14A in more than 2 cancer types. Because this analysis shows association rather than direction, both UTP14A-to-partner and partner-to-UTP14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by UTP14A-low versus UTP14A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP14A→partner) and Y-score (partner→UTP14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.464	+1.522	.008	.017	3	3
UCEC	c-Kit →	-0.151	-1.378	.029	.008	3	3
UCEC	FoxM1 →	+0.175	+1.378	.023	.008	3	2
UCEC	Mre11 →	-0.054	-1.973	.035	.029	3	2
UCEC	PCNA →	+0.174	+1.378	.006	.008	3	2
UCEC	S6_pS240_S244 →	+0.300	+2.713	.013	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Caspase-7-cleavedD198 by UTP14A expression — UCEC

Explore this box plot interactively →