UTP14A

Across TCGA cell cohorts, UTP14A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,846 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UTP14A-associated GO terms across cancer lineages are Maturation of SSU-rRNA, snRNA pseudouridine synthesis, and Termination of RNA polymerase I transcription. Each is linked with UTP14A in more than 15 cancer types. Because this analysis shows association rather than direction, both UTP14A-to-partner and partner-to-UTP14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by UTP14A-low versus UTP14A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP14A→partner) and Y-score (partner→UTP14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Maturation of SSU-rRNA →	+0.132	+1.092	<.001	.001	3	16
PANCREAS	snRNA pseudouridine synthesis →	+0.083	+0.737	<.001	<.001	3	16
OVARY	Termination of RNA polymerase I transcription →	+0.100	+0.694	<.001	.003	3	15
PANCREAS	Transcription initiation at RNA polymerase I promoter →	+0.134	+1.016	<.001	<.001	3	15
PANCREAS	scaRNA localization to Cajal body →	+0.124	+0.913	<.001	.001	3	15
LUNG_SCLC	Ribosome biogenesis →	+0.117	+0.642	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,846 associations by consensus.

Maturation of SSU-rRNA by UTP14A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →