UTP14A

Across TCGA cell cohorts, UTP14A mutation is significantly associated with the RNA expression of many other genes, with 220 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UTP14A-associated genes across cancer lineages are GALP, MS4A6E, and C16orf82. Each is linked with UTP14A in more than 1 cancer types. Because this analysis shows association rather than direction, both UTP14A-to-partner and partner-to-UTP14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALP grouped by UTP14A-low versus UTP14A-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP14A→partner) and Y-score (partner→UTP14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GALP →	+0.022	+5.415	<.001	.004	3	1
LUNG_NSCLC_LUAD	MS4A6E →	+0.044	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	C16orf82 →	+0.013	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	KRTAP10-11 →	+0.018	+4.887	<.001	.009	3	1
LARGE_INTESTINE	KXD1 →	+0.423	+3.299	.002	.004	3	1
LARGE_INTESTINE	SH3GL2 →	+1.168	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 220 associations by consensus.

GALP by UTP14A expression — SKIN

Explore this box plot interactively →