USPL1

Across TCGA patient cohorts, USPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,103 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible USPL1-associated genes across cancer lineages are SALL4, CHRDL1, and VIPR2. Each is linked with USPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both USPL1-to-partner and partner-to-USPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USPL1 versus SALL4 in GBM, with a Pearson correlation of -0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USPL1→partner) and Y-score (partner→USPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SALL4 →	-1.239	-0.890	.009	.009	3	1
GBM	CHRDL1 →	+2.468	+0.686	.001	.006	3	1
GBM	VIPR2 →	+2.195	+0.686	<.001	.006	3	1
GBM	EHHADH →	+0.562	+0.686	<.001	.006	3	1
GBM	AREL1 →	-0.986	-0.909	<.001	.008	3	1
GBM	GRHL1 →	+1.137	+0.686	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,103 associations by consensus.

USPL1 vs SALL4 — GBM

Explore this scatter interactively →