USP48

Across TCGA patient cohorts, USP48 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,301 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP48-associated proteins across cancer lineages are RPA1, PPP1R8, and RCC2. Each is linked with USP48 in more than 6 cancer types. Because this analysis shows association rather than direction, both USP48-to-partner and partner-to-USP48 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP48 versus RPA1 in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP48→partner) and Y-score (partner→USP48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPA1 →	+0.345	+0.367	<.001	<.001	3	7
GBM	PPP1R8 →	+0.211	+0.322	<.001	.001	3	6
GBM	RCC2 →	+0.474	+0.416	<.001	<.001	3	6
GBM	SPEN →	+0.204	+0.311	<.001	<.001	3	6
UCEC	SYF2 →	+0.324	+0.368	<.001	.001	3	6
GBM	DNAJC8 →	+0.242	+0.301	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,301 associations by consensus.

USP48 vs RPA1 — LSCC

Explore this scatter interactively →