USP47

Across TCGA cell cohorts, USP47 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,136 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USP47-associated GO terms across cancer lineages are Telomere tethering at nuclear periphery, Phosphatidylinositol biosynthetic process, and Cytosolic transport. Each is linked with USP47 in more than 14 cancer types. Because this analysis shows association rather than direction, both USP47-to-partner and partner-to-USP47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere tethering at nuclear periphery grouped by USP47-low versus USP47-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP47→partner) and Y-score (partner→USP47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Telomere tethering at nuclear periphery →	+0.180	+1.353	<.001	<.001	3	15
BONE	Phosphatidylinositol biosynthetic process →	+0.063	+0.625	<.001	<.001	3	13
STOMACH	Cytosolic transport →	+0.083	+1.091	.001	<.001	3	13
STOMACH	Negative regulation of organelle assembly →	+0.063	+1.010	.007	.002	3	13
OVARY	Monoubiquitinated protein deubiquitination →	+0.130	+1.007	<.001	<.001	3	13
BONE	Regulation of protein K48-linked ubiquitination →	+0.170	+0.618	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,136 associations by consensus.

Telomere tethering at nuclear periphery by USP47 expression — STOMACH

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