USP39

Across TCGA patient cohorts, USP39 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,726 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible USP39-associated proteins across cancer lineages are UTP4, KPNA2, and MCM2. Each is linked with USP39 in more than 8 cancer types. Because this analysis shows association rather than direction, both USP39-to-partner and partner-to-USP39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP39 versus UTP4 in LSCC, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP39→partner) and Y-score (partner→USP39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UTP4 →	+0.386	+0.704	<.001	<.001	3	9
LSCC	KPNA2 →	+0.490	+0.529	<.001	<.001	3	8
LSCC	MCM2 →	+0.613	+0.656	<.001	<.001	3	8
GBM	MCM2_S139 →	+0.817	+0.286	<.001	<.001	3	8
LSCC	MCM3 →	+0.684	+0.613	<.001	<.001	3	8
LSCC	MCM4 →	+0.657	+0.622	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,726 associations by consensus.

USP39 vs UTP4 — LSCC

Explore this scatter interactively →