USP39

Across TCGA patient cohorts, USP39 protein abundance is significantly associated with the RNA expression of many other genes, with 22,397 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible USP39-associated genes across cancer lineages are RAE1, F13A1, and TPX2. Each is linked with USP39 in more than 7 cancer types. Because this analysis shows association rather than direction, both USP39-to-partner and partner-to-USP39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP39 versus RAE1 in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP39→partner) and Y-score (partner→USP39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAE1 →	+0.628	+0.306	<.001	<.001	3	8
GBM	F13A1 →	-1.807	-0.280	<.001	<.001	3	8
LUAD	TPX2 →	+1.060	+0.136	<.001	.001	3	8
BRCA	CABLES2 →	+0.708	+0.311	<.001	<.001	3	7
BRCA	MYBL2 →	+1.247	+0.244	<.001	<.001	3	7
UCEC	CENPI →	+1.164	+0.322	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,397 associations by consensus.

USP39 vs RAE1 — UCEC

Explore this scatter interactively →