USP38

Across TCGA patient cohorts, USP38 protein abundance is significantly associated with the RNA expression of many other genes, with 6,501 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible USP38-associated genes across cancer lineages are DNAJC2, CCNY, and C12orf45. Each is linked with USP38 in more than 2 cancer types. Because this analysis shows association rather than direction, both USP38-to-partner and partner-to-USP38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP38 versus DNAJC2 in HNSC, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP38→partner) and Y-score (partner→USP38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DNAJC2 →	-1.406	-0.535	<.001	<.001	3	2
HNSC	CCNY →	-0.717	-0.313	.003	.002	3	2
HNSC	C12orf45 →	-0.635	-0.461	.001	<.001	3	2
HNSC	LINC01139 →	-1.339	-0.344	<.001	<.001	3	2
UCEC	LINC01312 →	-0.424	-0.170	<.001	<.001	3	2
HNSC	FOXP4-AS1 →	-1.336	-0.538	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,501 associations by consensus.

USP38 vs DNAJC2 — HNSC

Explore this scatter interactively →