USP38

Across TCGA patient cohorts, USP38 mutation is significantly associated with the RNA expression of many other genes, with 2,982 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible USP38-associated genes across cancer lineages are MIR6075, RACGAP1P1, and MIR4505. Each is linked with USP38 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP38-to-partner and partner-to-USP38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6075 grouped by USP38-low versus USP38-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP38→partner) and Y-score (partner→USP38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR6075 →	+0.313	+4.544	<.001	.009	3	2
LIHC	RACGAP1P1 →	+0.020	+4.544	<.001	.009	3	2
LIHC	MIR4505 →	+0.736	+6.734	<.001	<.001	3	2
LIHC	SAMD7 →	+0.019	+4.868	.003	.002	3	2
LIHC	RNU6-1311P →	+0.480	+4.776	<.001	.003	3	2
UCEC	BCCIP →	+0.340	+2.637	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,982 associations by consensus.

MIR6075 by USP38 expression — LIHC

Explore this box plot interactively →