USP38

Across TCGA cell cohorts, USP38 protein abundance is significantly associated with the RNA expression of many other genes, with 2,222 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible USP38-associated genes across cancer lineages are TMED3, FAM114A1, and HGSNAT. Each is linked with USP38 in more than 4 cancer types. Because this analysis shows association rather than direction, both USP38-to-partner and partner-to-USP38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP38 versus TMED3 in LUNG_NSCLC_LUSC, with a Pearson correlation of -0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP38→partner) and Y-score (partner→USP38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TMED3 →	-0.817	-0.723	.002	.002	3	5
LUNG_NSCLC_LUSC	FAM114A1 →	-2.457	-0.992	<.001	.001	3	5
BLOOD_Leukemia	HGSNAT →	-0.909	-0.577	.004	<.001	3	5
BLOOD_Lymphoma	LACC1 →	-1.234	-0.635	.002	.003	3	5
LUNG_NSCLC_LUSC	DAB2 →	-2.913	-0.776	<.001	<.001	3	4
LIVER	RAB8B →	-1.440	-1.176	.008	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,222 associations by consensus.

USP38 vs TMED3 — LUNG_NSCLC_LUSC

Explore this scatter interactively →