USP37

Across TCGA pan-cancer cohorts, USP37 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated USP37 data layer compared with 28 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher USP37 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated USP37 expression acts as an unfavorable survival marker.

KIRC, CESC, and KIRP are the cancer types where USP37 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.122	0.811	<.001	36	view →
CESC	OS	Median	II,III,IV	0.094	0.552	.002	14	view →
KIRP	OS	Median	II,III,IV	0.188	0.771	.016	10	view →
SARC	DFS	Median	All	0.094	0.632	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

USP37–KIRC (OS)

Open the KIRC breakdown →