USP34

Across TCGA patient cohorts, USP34 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,309 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible USP34-associated proteins across cancer lineages are SNRPD2, ZNF638, and RBBP5. Each is linked with USP34 in more than 5 cancer types. Because this analysis shows association rather than direction, both USP34-to-partner and partner-to-USP34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP34 versus SNRPD2 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP34→partner) and Y-score (partner→USP34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD2 →	+0.220	+0.230	.002	.003	3	6
GBM	ZNF638 →	+0.291	+0.508	<.001	<.001	3	5
HNSC	RBBP5 →	+0.309	+0.788	<.001	.001	3	5
LSCC	TIA1 →	+0.344	+0.500	<.001	<.001	3	5
LSCC	TRIM28 →	+0.353	+0.522	<.001	<.001	3	5
LSCC	TSN →	+0.257	+0.402	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,309 associations by consensus.

USP34 vs SNRPD2 — GBM

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