USP34

Across TCGA patient cohorts, USP34 protein abundance is significantly associated with the RNA expression of many other genes, with 10,872 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible USP34-associated genes across cancer lineages are CCT4, NOL10, and DTYMK. Each is linked with USP34 in more than 6 cancer types. Because this analysis shows association rather than direction, both USP34-to-partner and partner-to-USP34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP34 versus CCT4 in LSCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP34→partner) and Y-score (partner→USP34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CCT4 →	+0.611	+0.209	<.001	<.001	3	7
HNSC	NOL10 →	+0.839	+0.241	<.001	<.001	3	7
HNSC	DTYMK →	+1.059	+0.192	<.001	<.001	3	7
HNSC	CPSF3 →	+0.901	+0.200	<.001	<.001	3	7
UCEC	KIF23 →	+1.036	+0.176	<.001	<.001	3	7
UCEC	CDCA5 →	+1.125	+0.156	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,872 associations by consensus.

USP34 vs CCT4 — LSCC

Explore this scatter interactively →