USP34

Across TCGA cell cohorts, USP34 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,312 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USP34-associated GO terms across cancer lineages are Regulation of centrosome duplication, Positive regulation of organelle assembly, and Negative regulation of bicellular tight junction assembly. Each is linked with USP34 in more than 14 cancer types. Because this analysis shows association rather than direction, both USP34-to-partner and partner-to-USP34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centrosome duplication grouped by USP34-low versus USP34-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP34→partner) and Y-score (partner→USP34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of centrosome duplication →	+0.101	+0.848	<.001	.003	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.071	+0.892	<.001	<.001	3	14
SKIN	Negative regulation of bicellular tight junction assembly →	+0.146	+0.459	<.001	<.001	3	14
LUNG_SCLC	Regulation of microtubule-based process →	+0.074	+0.633	<.001	<.001	3	14
STOMACH	Epigenetic regulation of gene expression →	+0.069	+0.653	.004	.007	3	14
URINARY_TRACT	Regulation of centrosome cycle →	+0.098	+0.998	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,312 associations by consensus.

Regulation of centrosome duplication by USP34 expression — URINARY_TRACT

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