USP32

Across TCGA pan-cancer cohorts, USP32 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated USP32 data layer compared with 26 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher USP32 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated USP32 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where USP32 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	II,III,IV	1.000	0.412	.015	6	view →
PDAC	DFS	Median	II,III,IV	0.612	0.834	.025	5	view →
CCRCC	DFS	Median	All	0.849	0.590	.008	5	view →
LSCC	OS	Quartile	III,IV	0.444	0.925	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

USP32–LUAD (OS)

Open the LUAD breakdown →