USP29

Across TCGA cell cohorts, USP29 mutation is significantly associated with the RNA expression of many other genes, with 117 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible USP29-associated genes across cancer lineages are SOX14, C18orf63, and OR13C7. Each is linked with USP29 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP29-to-partner and partner-to-USP29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SOX14 grouped by USP29-low versus USP29-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP29→partner) and Y-score (partner→USP29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SOX14 →	+0.367	+4.392	<.001	.003	3	1
SOFT_TISSUE	C18orf63 →	+0.004	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR13C7 →	+0.028	+4.369	<.001	.008	3	1
STOMACH	NRAP →	+0.051	+4.169	<.001	.001	3	1
BLOOD_Leukemia	GUCA2A →	+0.039	+4.969	<.001	.003	3	1
BLOOD_Leukemia	FAM24A →	+0.064	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

SOX14 by USP29 expression — OESOPHAGUS

Explore this box plot interactively →