USP27X

Across TCGA patient cohorts, USP27X RNA expression is significantly associated with the protein abundance of many other proteins, with 15,527 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP27X-associated proteins across cancer lineages are TCEAL1, UNC13D, and RBM10. Each is linked with USP27X in more than 6 cancer types. Because this analysis shows association rather than direction, both USP27X-to-partner and partner-to-USP27X results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP27X versus TCEAL1 in BRCA, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP27X→partner) and Y-score (partner→USP27X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TCEAL1 →	+0.701	+0.370	.001	.006	3	7
GBM	UNC13D →	-0.527	-0.415	<.001	<.001	3	6
GBM	RBM10 →	+0.318	+0.329	<.001	.002	3	6
OV	HUWE1 →	+0.246	+0.505	<.001	<.001	3	6
LSCC	TCEAL4 →	+0.445	+0.613	<.001	<.001	3	6
CCRCC	SEC23B →	-0.383	-0.487	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,527 associations by consensus.

USP27X vs TCEAL1 — BRCA

Explore this scatter interactively →