USP27X

Across TCGA cell cohorts, USP27X RNA expression is significantly associated with the go_rna of many other GO terms, with 4,373 significant associations in total. BONE shows the largest number of these associations.

The most reproducible USP27X-associated GO terms across cancer lineages are Tubulin deacetylation, Growth hormone secretion, and Regulation of heterochromatin formation. Each is linked with USP27X in more than 12 cancer types. Because this analysis shows association rather than direction, both USP27X-to-partner and partner-to-USP27X results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tubulin deacetylation grouped by USP27X-low versus USP27X-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP27X→partner) and Y-score (partner→USP27X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Tubulin deacetylation →	+0.123	+0.611	.003	.006	3	13
PANCREAS	Growth hormone secretion →	+0.139	+0.806	<.001	<.001	3	12
OVARY	Regulation of heterochromatin formation →	+0.112	+0.974	<.001	<.001	3	12
STOMACH	Transport along microtubule →	+0.048	+0.719	.001	.003	2	13
LUNG_SCLC	Regulation of myoblast fusion →	+0.090	+1.340	.002	.001	3	11
OVARY	Heterochromatin formation →	+0.079	+0.827	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,373 associations by consensus.

Tubulin deacetylation by USP27X expression — BREAST

Explore this box plot interactively →