USP24

Across TCGA pan-cancer cohorts, USP24 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated USP24 data layer compared with 27 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher USP24 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated USP24 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LSCC, HNSC, and UCEC are the cancer types where USP24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.913	0.671	.019	12	view →
HNSC	OS	Median	IV	0.932	0.735	.009	7	view →
UCEC	DFS	Tertile	III,IV	1.000	0.457	.026	4	view →
PDAC	OS	Quartile	II,III,IV	0.668	0.982	.007	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

USP24–LSCC (OS)

Open the LSCC breakdown →