USP20

Across TCGA cell cohorts, USP20 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,294 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible USP20-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Transcription pausing by RNA polymerase II. Each is linked with USP20 in more than 16 cancer types. Because this analysis shows association rather than direction, both USP20-to-partner and partner-to-USP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by USP20-low versus USP20-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP20→partner) and Y-score (partner→USP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.105	+0.886	<.001	<.001	3	17
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.103	+0.846	<.001	<.001	3	17
STOMACH	Transcription pausing by RNA polymerase II →	+0.121	+0.892	.002	.005	3	16
STOMACH	Process utilizing autophagic mechanism →	+0.101	+1.299	<.001	<.001	3	15
STOMACH	Autophagy →	+0.101	+1.299	<.001	<.001	3	15
STOMACH	Regulation of myoblast fusion →	+0.162	+1.151	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,294 associations by consensus.

Negative regulation of myoblast fusion by USP20 expression — STOMACH

Explore this box plot interactively →