USP2

Across TCGA cell cohorts, USP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,970 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USP2-associated GO terms across cancer lineages are Cytoplasmic translation, DNA-templated transcription initiation, and Nucleoside triphosphate metabolic process. Each is linked with USP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both USP2-to-partner and partner-to-USP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by USP2-low versus USP2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP2→partner) and Y-score (partner→USP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cytoplasmic translation →	+0.090	+1.470	.001	<.001	3	11
BONE	DNA-templated transcription initiation →	+0.078	+1.128	<.001	<.001	3	10
SKIN	Nucleoside triphosphate metabolic process →	+0.093	+0.834	<.001	<.001	3	9
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.137	+1.120	.006	.001	3	9
STOMACH	Positive regulation of translation →	+0.073	+1.354	<.001	<.001	3	9
STOMACH	Regulation of transcription initiation by RNA polymerase II →	+0.052	+1.213	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,970 associations by consensus.

Cytoplasmic translation by USP2 expression — STOMACH

Explore this box plot interactively →