USP17L8

Across TCGA patient cohorts, USP17L8 RNA expression is significantly associated with the protein abundance of many other proteins, with 1,466 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible USP17L8-associated proteins across cancer lineages are SH3D19_S275, CCDC6_S52, and DNMT1_S154. Each is linked with USP17L8 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L8-to-partner and partner-to-USP17L8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP17L8 versus SH3D19_S275 in LUAD, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L8→partner) and Y-score (partner→USP17L8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SH3D19_S275 →	+0.366	+0.019	.009	.002	3	2
LUAD	CCDC6_S52 →	-0.618	-0.025	.003	.002	3	2
LUAD	DNMT1_S154 →	-0.727	-0.040	.001	.002	3	2
LUAD	DYNC1LI2_S443 →	-0.755	-0.025	.006	.002	3	2
LUAD	PIK3C2B_S155 →	+0.324	+0.025	.003	<.001	3	2
LUAD	PSME3_S24 →	-1.042	-0.022	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,466 associations by consensus.

USP17L8 vs SH3D19_S275 — LUAD

Explore this scatter interactively →