USP17L8

Across TCGA cell cohorts, USP17L8 RNA expression is significantly associated with the mutation status of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USP17L8-associated genes across cancer lineages are MS4A4A, KRT75, and OR4D9. Each is linked with USP17L8 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L8-to-partner and partner-to-USP17L8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A4A grouped by USP17L8-low versus USP17L8-high in URINARY_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L8→partner) and Y-score (partner→USP17L8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	MS4A4A →	+4.087	+0.005	.009	<.001	3	1
URINARY_TRACT	KRT75 →	+4.087	+0.005	.009	<.001	3	1
URINARY_TRACT	OR4D9 →	+4.087	+0.005	.009	<.001	3	1
URINARY_TRACT	NGFR →	+5.087	+0.006	.004	<.001	3	1
SOFT_TISSUE	ASB2 →	+4.977	+0.010	.002	<.001	3	1
SOFT_TISSUE	GNPTAB →	+4.977	+0.010	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

MS4A4A by USP17L8 expression — URINARY_TRACT

Explore this box plot interactively →