Across TCGA pan-cancer cohorts, USP17L7 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated USP17L7 data layer compared with 13 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher USP17L7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated USP17L7 expression acts as an unfavorable survival marker.

LUSC and UCEC are the cancer types where USP17L7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	III,IV	0.126	0.664	.008	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: USP17L7 tumor-vs-normal RNA expression · all USP17L7 data types