USP17L22

Across TCGA patient cohorts, USP17L22 RNA expression is significantly associated with the go_rna of many other GO terms, with 45 significant associations in total. OV shows the largest number of these associations.

The most reproducible USP17L22-associated GO terms across cancer lineages are Regulation of myeloid cell differentiation, Negative regulation of myeloid cell differentiation, and Protein modification by small protein removal. Each is linked with USP17L22 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L22-to-partner and partner-to-USP17L22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myeloid cell differentiation grouped by USP17L22-low versus USP17L22-high in OV.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L22→partner) and Y-score (partner→USP17L22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	Regulation of myeloid cell differentiation →	+0.040	+0.001	.005	.006	2	1
OV	Negative regulation of myeloid cell differentiation →	+0.040	+0.002	.006	.007	2	1
OV	Protein modification by small protein removal →	+0.045	+0.003	.004	.006	2	1
OV	Response to reactive oxygen species →	+0.037	+0.001	.003	.005	2	1
OV	Obsolete ncRNA transcription →	+0.043	+0.003	.003	.006	2	1
OV	Positive regulation of cysteine-type endopeptidase activity →	+0.038	+0.001	.003	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Regulation of myeloid cell differentiation by USP17L22 expression — OV

Explore this box plot interactively →