USP17L22

Across TCGA cell cohorts, USP17L22 RNA expression is significantly associated with the mutation status of many other genes, with 114 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible USP17L22-associated genes across cancer lineages are MSH5, COL4A5, and CDCP2. Each is linked with USP17L22 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L22-to-partner and partner-to-USP17L22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSH5 grouped by USP17L22-low versus USP17L22-high in OESOPHAGUS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L22→partner) and Y-score (partner→USP17L22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MSH5 →	+4.392	+0.027	.003	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	COL4A5 →	+4.357	+0.010	.006	<.001	3	2
LUNG_NSCLC_LUAD	CDCP2 →	+4.947	+0.018	.001	<.001	3	2
LUNG_NSCLC_LUAD	DNAH7 →	+2.225	+0.008	.003	.002	3	2
BLOOD_Lymphoma	CAMK1G →	+4.643	+0.019	.005	<.001	3	1
BLOOD_Lymphoma	CFH →	+4.643	+0.019	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 114 associations by consensus.

MSH5 by USP17L22 expression — OESOPHAGUS

Explore this box plot interactively →