Across TCGA patient cohorts, USP17L2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,571 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP17L2-associated proteins across cancer lineages are LARP4_S583, RPL5, and RPS23. Each is linked with USP17L2 in more than 3 cancer types. Because this analysis shows association rather than direction, both USP17L2-to-partner and partner-to-USP17L2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L2→partner) and Y-score (partner→USP17L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LARP4_S583 →	-0.398	-0.514	<.001	<.001	3	4
GBM	RPL5 →	-0.182	-0.787	<.001	.001	3	3
GBM	RPS23 →	-0.224	-0.821	.002	.004	3	3
GBM	RPSA →	-0.162	-1.152	<.001	<.001	3	3
LSCC	UGDH_S476 →	-0.770	-0.460	.001	.004	3	3
PDAC	OAS2_S466 →	-1.333	-0.515	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,571 associations by consensus.

Exploration

USP17L2 survival (RNA) · tumor vs normal (RNA) · all USP17L2 data types