Across TCGA patient cohorts, USP17L2 mutation is significantly associated with the RNA expression of many other genes, with 479 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible USP17L2-associated genes across cancer lineages are OR8D2, GJD4, and RN7SL83P. Each is linked with USP17L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L2-to-partner and partner-to-USP17L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L2→partner) and Y-score (partner→USP17L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR8D2 →	+0.028	+5.033	<.001	.003	3	2
UCEC	GJD4 →	+0.186	+3.472	.002	.006	3	2
COAD	RN7SL83P →	+0.310	+4.070	<.001	.009	3	2
SKCM	SNORD62A →	+0.439	+2.034	.001	.004	3	2
SKCM	SNORA47 →	+0.485	+2.379	.002	.003	3	2
BLCA	MIRLET7F1 →	+0.474	+3.830	.005	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 479 associations by consensus.

Exploration

USP17L2 survival (RNA) · tumor vs normal (RNA) · all USP17L2 data types