USP17L2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, USP17L2 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible USP17L2-associated genes across cancer lineages are G6PD, XBP1, and Cyclin-B1. Each is linked with USP17L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L2-to-partner and partner-to-USP17L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L2→partner) and Y-score (partner→USP17L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMG6PD →-0.221-2.584.022.01131
SKCMXBP1 →-0.223-2.584.049.01131
SKCMCyclin-B1 →+0.454+2.584.016.01131
SKCMA-Raf_pS299 →-0.138-2.584.038.01121
SKCMCaveolin-1 →-0.665-3.000.020.03521
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

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