Across TCGA cell cohorts, USP17L2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USP17L2-associated genes across cancer lineages are SLC17A4, OR4K2, and OPCML. Each is linked with USP17L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L2-to-partner and partner-to-USP17L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L2→partner) and Y-score (partner→USP17L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC17A4 →	+0.079	+4.152	<.001	.009	3	1
BLOOD_Leukemia	OR4K2 →	+0.031	+4.969	<.001	.003	3	1
BLOOD_Leukemia	OPCML →	+0.146	+4.152	<.001	.009	3	1
BLOOD_Leukemia	S100A7A →	+0.042	+4.152	<.001	.009	3	1
BLOOD_Leukemia	CGB8 →	+0.073	+4.551	<.001	.004	3	1
LARGE_INTESTINE	DBX2 →	+0.023	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

USP17L2 survival (RNA) · tumor vs normal (RNA) · all USP17L2 data types