Across TCGA patient cohorts, USP17L15 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible USP17L15-associated genes across cancer lineages are RNA5SP64, OR4F4, and RNU6-294P. Each is linked with USP17L15 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L15-to-partner and partner-to-USP17L15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L15→partner) and Y-score (partner→USP17L15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP64 →	+0.276	+7.924	<.001	.008	3	2
SKCM	OR4F4 →	+0.048	+6.797	<.001	<.001	3	2
LUSC	RNU6-294P →	+0.288	+7.924	.003	.008	3	1
LUSC	RNU6ATAC19P →	+0.272	+7.924	<.001	.008	3	1
LUSC	RNU6-67P →	+0.301	+7.924	<.001	.008	3	1
LUSC	RN7SKP142 →	+0.117	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

USP17L15 survival (RNA) · tumor vs normal (RNA) · all USP17L15 data types