USP17L10

Across TCGA patient cohorts, USP17L10 protein abundance is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP17L10-associated genes across cancer lineages are PDGFRA, AGRP, and SPRYD4. Each is linked with USP17L10 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L10-to-partner and partner-to-USP17L10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP17L10 versus PDGFRA in GBM, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L10→partner) and Y-score (partner→USP17L10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PDGFRA →	-0.996	-2.126	.001	.009	3	1
GBM	AGRP →	-0.870	-2.804	<.001	.008	3	1
GBM	SPRYD4 →	-0.599	-2.804	.002	.008	3	1
GBM	ABCA4 →	+0.396	+2.116	.001	.009	3	1
GBM	LINC01343 →	+0.183	+2.923	.004	.004	3	1
GBM	FOXD1 →	-1.493	-2.530	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

USP17L10 vs PDGFRA — GBM

Explore this scatter interactively →