USP13

Across TCGA patient cohorts, USP13 protein abundance is significantly associated with the RNA expression of many other genes, with 21,210 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible USP13-associated genes across cancer lineages are ZC3HAV1L, PEX5L, and SLC30A3. Each is linked with USP13 in more than 4 cancer types. Because this analysis shows association rather than direction, both USP13-to-partner and partner-to-USP13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP13 versus ZC3HAV1L in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP13→partner) and Y-score (partner→USP13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZC3HAV1L →	+0.864	+0.336	<.001	<.001	3	5
BRCA	PEX5L →	+0.682	+0.290	<.001	<.001	3	5
LSCC	SLC30A3 →	+0.507	+0.400	<.001	<.001	3	4
HNSC	ARHGEF2 →	+0.539	+0.362	<.001	<.001	3	4
LSCC	ABCB9 →	+0.587	+0.533	<.001	<.001	3	4
HNSC	MAP1A →	+0.953	+0.327	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,210 associations by consensus.

USP13 vs ZC3HAV1L — HNSC

Explore this scatter interactively →