Across TCGA pan-cancer cohorts, USP12P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of USP12P2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where USP12P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types USP12P2 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

KIRC, BRCA, and LUSC are the cancer types where USP12P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in USP12P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.019	<.001	4	view →
BRCA	Female	All	+0.143	.040	2	view →
LUSC	Female	III,IV	−0.095	.002	1	view →
KIRP	All	All	+0.042	.019	1	view →
THCA	Female	All	−0.027	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: USP12P2 RNA expression & survival · all USP12P2 data types