USP10

Across TCGA pan-cancer cohorts, USP10 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated USP10 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher USP10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated USP10 expression acts as an unfavorable survival marker, although some lineages such as LUAD and COAD show a favorable association.

LUAD, PDAC, and COAD are the cancer types where USP10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.993	0.642	.001	51	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	20	view →
COAD	DFS	Median	II,III,IV	1.000	0.884	.025	18	view →
GBM	OS	Median	All	0.464	0.301	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

USP10–LUAD (DFS)

Open the LUAD breakdown →