USP10

Across TCGA patient cohorts, USP10 mutation is significantly associated with the RNA expression of many other genes, with 3,150 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible USP10-associated genes across cancer lineages are RNA5SP412, ERHP2, and LINC02002. Each is linked with USP10 in more than 2 cancer types. Because this analysis shows association rather than direction, both USP10-to-partner and partner-to-USP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by USP10-low versus USP10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP10→partner) and Y-score (partner→USP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.416	+1.667	<.001	<.001	3	3
LIHC	ERHP2 →	+0.152	+5.647	<.001	.004	3	3
READ	LINC02002 →	+0.033	+4.925	<.001	.004	3	3
UCEC	PPIP5K1 →	+0.246	+1.331	.005	.002	3	3
LIHC	PER3P1 →	+0.148	+5.355	<.001	.005	3	2
CESC	LINC02514 →	+0.105	+4.812	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,150 associations by consensus.

RNA5SP412 by USP10 expression — UCEC

Explore this box plot interactively →