USP10

Across TCGA cell cohorts, USP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,113 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible USP10-associated GO terms across cancer lineages are snRNA 3'-end processing, snRNA processing, and mRNA export from nucleus. Each is linked with USP10 in more than 17 cancer types. Because this analysis shows association rather than direction, both USP10-to-partner and partner-to-USP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snRNA 3'-end processing grouped by USP10-low versus USP10-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP10→partner) and Y-score (partner→USP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	snRNA 3'-end processing →	+0.085	+1.230	.006	.002	3	18
BREAST	snRNA processing →	+0.083	+0.806	<.001	<.001	3	17
BONE	mRNA export from nucleus →	+0.149	+0.793	<.001	.002	3	17
BONE	snRNA metabolic process →	+0.076	+0.664	.003	.001	3	16
BONE	Nucleocytoplasmic transport →	+0.077	+0.631	<.001	<.001	3	16
BONE	Nuclear transport →	+0.078	+0.631	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,113 associations by consensus.

snRNA 3'-end processing by USP10 expression — BLOOD_Myeloma

Explore this box plot interactively →