USH1G

Across TCGA cell cohorts, USH1G mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USH1G-associated genes across cancer lineages are MTRNR2L6, GPR26, and CYP3A43. Each is linked with USH1G in more than 1 cancer types. Because this analysis shows association rather than direction, both USH1G-to-partner and partner-to-USH1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTRNR2L6 grouped by USH1G-low versus USH1G-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USH1G→partner) and Y-score (partner→USH1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MTRNR2L6 →	+0.080	+4.269	<.001	.002	3	2
LUNG_NSCLC_LUAD	GPR26 →	+0.008	+3.813	<.001	.001	3	1
LUNG_NSCLC_LUAD	CYP3A43 →	+0.072	+3.009	.005	.006	3	1
BLOOD_Lymphoma	BANF2 →	+0.035	+4.643	.003	.005	3	1
BLOOD_Lymphoma	LMX1A →	+0.024	+4.714	.004	.002	3	1
BLOOD_Lymphoma	SPINK6 →	+0.935	+4.927	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

MTRNR2L6 by USH1G expression — BLOOD_Leukemia

Explore this box plot interactively →