USF3

Across TCGA cell cohorts, USF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,481 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USF3-associated GO terms across cancer lineages are Protein localization to chromosome, telomeric region, Phosphatidylinositol-3-phosphate biosynthetic process, and Regulation of organelle assembly. Each is linked with USF3 in more than 11 cancer types. Because this analysis shows association rather than direction, both USF3-to-partner and partner-to-USF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome, telomeric region grouped by USF3-low versus USF3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USF3→partner) and Y-score (partner→USF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein localization to chromosome, telomeric region →	+0.122	+0.928	<.001	<.001	3	12
OVARY	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.061	+0.609	.001	.005	3	12
OVARY	Regulation of organelle assembly →	+0.037	+0.558	<.001	<.001	3	11
OVARY	Positive regulation of cytoplasmic translation →	+0.121	+0.554	<.001	<.001	3	11
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.068	+0.727	.001	.006	2	12
PANCREAS	Peptidyl-serine phosphorylation →	+0.079	+0.605	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,481 associations by consensus.

Protein localization to chromosome, telomeric region by USF3 expression — LUNG_SCLC

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