USF2

Across TCGA patient cohorts, USF2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,562 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USF2-associated genes across cancer lineages are EID2B, ZNF227, and ZNF180. Each is linked with USF2 in more than 3 cancer types. Because this analysis shows association rather than direction, both USF2-to-partner and partner-to-USF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USF2 versus EID2B in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USF2→partner) and Y-score (partner→USF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EID2B →	+0.517	+0.224	.001	.001	3	4
GBM	ZNF227 →	+0.509	+0.242	<.001	<.001	3	4
GBM	ZNF180 →	+0.564	+0.297	<.001	<.001	3	4
BRCA	ZNF875 →	+0.534	+0.307	<.001	<.001	3	4
HNSC	ZNF546 →	+0.502	+0.132	<.001	<.001	3	4
HNSC	ZNF420 →	+0.861	+0.170	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,562 associations by consensus.

USF2 vs EID2B — GBM

Explore this scatter interactively →