Across TCGA pan-cancer cohorts, USF1P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of USF1P1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where USF1P1 RNA is repressed in tumor relative to normal tissue. In most cancer types USF1P1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, UCEC, and KIRC are the cancer types where USF1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in USF1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−0.108	.003	4	view →
UCEC	All	IV	+0.270	.032	2	view →
KIRC	Female	II,III,IV	−0.062	.028	1	view →
LIHC	All	II,III,IV	−0.032	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: USF1P1 RNA expression & survival · all USF1P1 data types