USF1

Across TCGA cell cohorts, USF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,886 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USF1-associated GO terms across cancer lineages are Hexose mediated signaling, Sugar mediated signaling pathway, and Glucose mediated signaling pathway. Each is linked with USF1 in more than 13 cancer types. Because this analysis shows association rather than direction, both USF1-to-partner and partner-to-USF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hexose mediated signaling grouped by USF1-low versus USF1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USF1→partner) and Y-score (partner→USF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Hexose mediated signaling →	+0.209	+1.051	.002	.003	3	14
URINARY_TRACT	Sugar mediated signaling pathway →	+0.209	+1.051	.002	.003	3	14
URINARY_TRACT	Glucose mediated signaling pathway →	+0.209	+1.051	.002	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.062	+0.639	<.001	<.001	3	12
KIDNEY	Carbohydrate mediated signaling →	+0.241	+0.505	.002	.003	3	11
BONE	Regulation of chromatin organization →	+0.121	+0.760	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,886 associations by consensus.

Hexose mediated signaling by USF1 expression — URINARY_TRACT

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