Across TCGA patient cohorts, UROS RNA expression is significantly associated with the protein abundance of many other proteins, with 13,507 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UROS-associated proteins across cancer lineages are GLRX3, CACUL1, and UBN2. Each is linked with UROS in more than 5 cancer types. Because this analysis shows association rather than direction, both UROS-to-partner and partner-to-UROS results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UROS→partner) and Y-score (partner→UROS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GLRX3 →	+0.392	+0.385	<.001	<.001	3	6
BRCA	CACUL1 →	+0.303	+0.413	<.001	<.001	3	5
LUAD	UBN2 →	+0.314	+0.319	<.001	<.001	3	4
CCRCC	VPS35 →	+0.165	+0.251	<.001	<.001	3	4
GBM	CCDC6 →	+0.240	+0.262	<.001	<.001	3	4
COAD	DDX21 →	+0.463	+0.390	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,507 associations by consensus.

Exploration

UROS survival (RNA) · tumor vs normal (RNA) · all UROS data types