URM1

Across TCGA cell cohorts, URM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,047 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible URM1-associated GO terms across cancer lineages are Dolichol phosphate mannose biosynthetic process, Positive regulation of mRNA 3'-end processing, and RNA export from nucleus. Each is linked with URM1 in more than 16 cancer types. Because this analysis shows association rather than direction, both URM1-to-partner and partner-to-URM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dolichol phosphate mannose biosynthetic process grouped by URM1-low versus URM1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (URM1→partner) and Y-score (partner→URM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Dolichol phosphate mannose biosynthetic process →	+0.124	+1.320	.005	<.001	3	17
BLOOD_Lymphoma	Positive regulation of mRNA 3'-end processing →	+0.104	+0.770	<.001	<.001	3	15
BONE	RNA export from nucleus →	+0.122	+0.514	<.001	<.001	3	13
LUNG_SCLC	Spliceosomal tri-snRNP complex assembly →	+0.121	+0.880	<.001	<.001	3	13
OESOPHAGUS	CTP salvage →	+0.158	+1.094	<.001	.009	2	14
OVARY	Response to oscillatory fluid shear stress →	+0.121	+0.525	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,047 associations by consensus.

Dolichol phosphate mannose biosynthetic process by URM1 expression — OESOPHAGUS

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